The sign at the Down Syndrome Organization of Southern Nevada was found riddled with bullets.
"We're afraid for the children," said the organization's Cheryl Allen, "we shouldn't have to be and we are."
The discovery was made Saturday outside the center on Vegas Drive near Decatur.
"It makes you mad," said Allen.
The sign is just steps away from the front door of the building. No one was injured in the incident.
"We could have not been closed, children are in and out of here all the time," said Allen.
Some fear the organization was targeted and worry that it may happen again.
"I hope it was just random," said Allen, "we would like to know if it's some kind of a message."
The organization helps families by providing therapy, classes, and various activities.
Deborah Avery's daughter has attended the center for nearly a decade.
"These kids are so special," said Avery, "they add so much to your life."
Avery has since become a board member. She's asking the public to come forward if they have any information on this case.
"We don't know if it's happened to somebody else," she said.